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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d60c08ea8dd0957d2937bd7dd388252da5ea150164f0af0f0663f21d05cb509' 
  AND token = 'RX9p8Aw071MmH/O/yi+d77K9PjAiZvwrxbwRluEttXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}