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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70c1000b8d06483440beb3d0d634eb9e3d4e791fef83044e6a71d2a38a08d0c7' 
  AND token = 'A8NgL7MLrqq9YXHoGIm5sInQp+POENJp29qO/chwhZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}