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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a66b1120cde603f0c056a2aeea418c20440dae12dd4ace1ce9290ac2c27e78b0' 
  AND token = 'jK2qmSUWEM07JA9gkg3I5+EM0foFAxEa6w4k+sQ6ai0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}