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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d1d5bcfe83555d23bb154531970ed46cbf5268f0e5e3dbe730b639deab3a2a7' 
  AND token = 'VGx+gqO7FadPZiWgiDRqiQqmDQ3olt/3IwrCvCVc9sw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}