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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e69f1523dd32fd26c4e0675a2e5085be9ba9b6c8487ba33f7007dd42252f9b2' 
  AND token = 'JePf35ToNEX8Pe0khkwpA+E4wc6xcBZOEGQviNR1ggQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}