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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a5ef76e39b13d0f48c590aa7a8fb8e251633cd3627415d344f104e7022e1d6a' 
  AND token = 'QMwGcu7Q6HiTifh/SUTu1zQnlNY3D6yzH1uwIylSzMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}