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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3eb65378a627accf2f8efcb6c899404c48cd1520bdd860facf778a2af7f3b467' 
  AND token = 'dj//FznKF1aHpbRKeoErkdaPypkIgjSJN1I23iQxA1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}