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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85d0c388caa6b7de1dfb9a07bfc386ffe669cf3042f98bef89da85d2d80328e5' 
  AND token = 'ndBdrOyEy/D5OtRx2vbdbVXT5ZzbZM8YPLK5cA70N6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}