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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '888ce2588f80479d130fa2e6c129964018f24d53c4f5381291c6ce2c287cdf2e' 
  AND token = '70JhRwwEQUoZEQZS8oe2MBJwgIyxv5577be6ODNwoPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}