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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de8e2a001ae2842984d057e76f6e1ad7ee8e10c8910c591c591d0753f2c75a41' 
  AND token = 'FHhMRSuvlk/Rg6T47DvR1a8QUDT05HIzzM67HcRRVQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}