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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5816fe0f0d10a7d1b4d23a37376e9d1443d323149115e172519bb00fd11ff6c7' 
  AND token = 'gmdHPm9AenRCHPV0YanBGgdjKfjvMydJ6iFPNZe6vGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}