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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78ab2492541eb0a8fbcde51eebbff89c8b9106242bb22820e5528f919a4bd741' 
  AND token = 'cUVSKcnjne7/l+sGEt+cJ44g1fsZ7EU0Y7WrkcW0VnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}