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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12f6e006a48257cda2a5631c18b72fa624cb3cb65bc7af08664783e5b5df1901' 
  AND token = 'A29oM4ttkevckkRxTRkPx91sQsjA7hQVM5uUD08J5Lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}