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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e16ea763d4d4f187b3000c6aab6c9b2952f5694d1ebc0f8095918b2bd6ebf553' 
  AND token = 'py2ii8sH+fkMpIGd+3i5vDgAWX42Vtkw81lL6nJ9rpY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}