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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c3a4f298517e73cf67acac954c9a47448b11c98ec87963368a7bce65fb6d15e' 
  AND token = 'MwJ+UCGL8xaUUNNGCviy+0dUNMbgqsmkPI7QHj5htyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}