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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea177acf3de4826ffa4b0eff42df63032691a23c6febfc63caa99bb535bcb8c7' 
  AND token = 'ghYPJkPgNrHmma9Vdh6p9uJC6GSrSNwHCb5ZqWe1P20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}