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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bc00ad9cf7a7a812304ce19c5df13442eb6be16271c7a213905253f0ca164fc' 
  AND token = '5+Plfw1s2uW+06cbKJDeXi0gyo/Ud2KF53dZv+wDjXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}