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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6807f5d6f07ea1a15db5daa668b8fcafb41b67e8394322708afe72b05980d7c' 
  AND token = 'xLXAURdd+b+B7R9ze6sRmK8yb6FGidV5TmGXv243aZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}