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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '657785ce308c64b469779b5435eb034424e29647de7a2d2b458aae9e19da8782' 
  AND token = 'oCq7MKySm4OMRMWcTmqGIZgTDERhO4JA+/u2b/4vYlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}