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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cee189cc9782da08b0ab860f0863ddf72cfb12924368ac6c64d5b5fcc3ec2a59' 
  AND token = '3IK8fF2QtEWNUEKwRpkhxADabRUMUgvIQOjyXUFjJ8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}