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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccbd56dd1db4f8a54b24f022ea381aa5d00f85d576620785a1fa246f78c3d13a' 
  AND token = 'pvLA9D6Tfg/RFUnzcfIqnKYYltUi5iETwyis5t0cnbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}