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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea99bc4e609d8578dd951b2b2a9e6bcddab4cc8b27495790453d887ece8484f5' 
  AND token = '+lqEfcgPIC3VD42eM3cIcmlNIc3DhmuSf02uz4CSnjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}