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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a86688756cde5fcf12b85ca2ba679aaed077b2a9db122fe6aaed5064a2f2ca1a' 
  AND token = 'khKT/KBX7ALrO4XFlK8uIDOkMiFfmBDQbnqpB4cFj5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}