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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '372473a42b01677d66eff28ec4b9979fbd4afbba4941ff538d22f8da9b015e6a' 
  AND token = 'ZbQOrIkcnF2QiMOa+u5CvSK9M3ddvU5JrCMSGY0CAqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}