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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd01d9b74d9e9abaac53b229b80604f19b467f399d6fb0be0a7f8640e64256bcc' 
  AND token = '4yGnqId361tGr54FC9FBFt+ltM8u20GFGWXtEmyyLow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}