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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '734b87885bd4e05d1bf638e2045deb47a4a77f2847338c4dcf4b5f036ed0b9d4' 
  AND token = 'FYcIe54lG8qwRn/YcCNe3v8ncN34RlLnSZv197ejAxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}