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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d50d3154eb541c961eeb59dd2db0330f7c8775f4d78ccf2c6934a4270e09ea1' 
  AND token = 'L0lxGScwmCn0eoTkCOzyAT8/uwvkHi8AKDE2gI/BhuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}