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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '818c4df729bfc6f2fe768c76a0e2aaf5db7ee2b40f6e4848f3055ca8a7eb7035' 
  AND token = 'WF4I4yrpyxud96pFiImtNxbUi60flOEm+gXwpIAxxCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}