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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47eb574ff08b0e43f3230df5e1177bdf03af1d6fb1f55cb5372faf1514e346f6' 
  AND token = 'rNkyB55KfFPYhjwS73w8aE0m4w3NnnABq4gDSDEii7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}