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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e47325c9e3935f133f1defb95f15a9c832ae0a35fbc61e53a378bc8bf3108803' 
  AND token = 'GPpFsmCFP9bI1uEBJ6/oqTa+ce4geGHN2lMkUxWGZg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}