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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f863faad4e7391a64a1d0ad50bae48fe774b8036378539246b8eb3ed99f6d6d2' 
  AND token = 'afNKU4LrvdAhPWEHNr/s02yoI/xpSxpn2OcVTgriG4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}