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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '192656952bb6e8c733dc027d98fff9dd38610c3e947bc48a540e7931a03c894f' 
  AND token = 'dsEDsNqcS0JyBKjqSdiHxzQHXrqEUd2pHdZjNAn6+MA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}