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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4148ff0d76455818b4f836fbd925ad0310bac75765a2feb8125ba11cf30b05c3' 
  AND token = 'xqcNKN1gj3lb9K9pUqKz9oc6000ZP+DKlzM9j7fJPgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}