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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5745c3d4792293f541dbe04d8e27df432933a49e98034daea3cc30e42d90099a' 
  AND token = '0LsumqGKmtoskrhxnhfX/d5v1YLyivfifwlZDK5ZXPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}