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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04ef781e78dd54c13d3f018fbbd22c623ceeb77508be33416b9079acd36e4ff4' 
  AND token = '/OGeZqHKVSFhglS0osCNophhENWaB8mX1C6Idg3mF8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}