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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48cba0e1662e780d0d416b336b478c41c7bb447bc92c1a0e7384004c8d176693' 
  AND token = 'thKzS2Io/fN759rQozLGlBKIEMMXyM5pQSWggSQg1q0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}