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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53f3a96694f8be0c5bf0d13e448caf432aded28007c63a88195152c31d0dabde' 
  AND token = 'epidcxa7OxaE7TzX64vE7Rfe8Hkc3ga5B1FafWaVafQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}