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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2039df1058e5adb3100a2285219199038c2a1c2c0083aea8a5a23b165ca0e277' 
  AND token = 'a+vkSfEOHUYj68uel1+zzLv3V4xqfgWTf0+dcEWuCWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}