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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdab444b9f5c72cdd39663a4b9219261b30e66e73501f959a15ac4cae7562d8a' 
  AND token = 'IsKk7zbd/08TYrpcaYA3fZMno3TFuOZkH4xnYQ5Jatg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}