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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4e6ec51cbc2d20939379dacf6c869e6376284a25023b909c0e6c781837f30c1' 
  AND token = 'tk6BVZDNkB3JFL0UxVwjAJ7AqaXNnTX22kaiAF7s6T8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}