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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efc4d9fd5777322a20443c1d8a02ad4647351fd57ea9420e6dfd5de506441270' 
  AND token = 'b83sab6EiYSJgJG+NmKsPuz2PYoMbidv5SVasHLKOKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}