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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2d8ac33315f4aece9917c232aef15432a22be336b531249248662a6438509dd' 
  AND token = 'euCVKI+3VzPkKQqkAZP/iiPDkiFVl4uH7tmLJ4w6qCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}