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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '669a383ecd66a2cbf8baa2b084a72cda9a81fd1adcb2a9a3e36231effbba1844' 
  AND token = 'By6VfY+dHQKAMS+fxH1PgEWxybgUArz/wdlLeJq+LeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}