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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b3c27c5c3d2a5dcd585fe7b9d2ce34dbe6f7f64d9b8e6d31cd6f7a0bd3d8563' 
  AND token = 'UyY/JqKW3cEEs6+1UbrUqoOoAVZ3C0z+i/vB9nGsUPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}