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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1de3aa0cc77fd7df739b4e1713abc22cbf0709f9fb3d44607af98d0449e30b6' 
  AND token = 'DSJM/67DGOO+dxNcZxcREV0PyhMwLv8QYTfMI8NbP0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}