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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c53b1dc61da2389b57c20b9ce2b7607c659a2dae70c4a7cd126f9d56b0cb451' 
  AND token = 'YOVzBpl+RKQT3MW83SWNfV7wWlUfy2KDQhbkkzc821U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}