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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f8c0684424df47763f8e4d914fd12dbc960a9096e77637fa4a75211fbbc4136' 
  AND token = 'vvDfSOJEqh4RTnVtVUrglL5sbJc6n1J4Z1yx0XVg6pg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}