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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e24e58493038fca27e70021700f77985ac20987109a86b1d0da02f71f1d9a90e' 
  AND token = '5Z9exr9OJAxDYzs7+CJIKb9pw6sikIDPnm2dYDYbvsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}