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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4ab21eb8410a4773267b2ba8eef7ebc1012c66ceaa85917a17b368507bef8f3' 
  AND token = 'YDk9L5Sgn7+oy3rFsjzjCXySu6kTRPdpMA8XnArAGm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}