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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f4501b73a00d0aebeecaa9565986150661386c7a067993cd8cd19a0df610501' 
  AND token = 'SuBnhe+bLomJRZqjpnySD3epU0+kcsN67pTkssrFcQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}